Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 130, Issue 11, Pages 3302-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja8009428
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- NIGMS NIH HHS [R01-GM62871] Funding Source: Medline
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The first catalytic asymmetric cross-coupling of alpha-halo carbono compounds with aryl metal reagents has been developed, thereby generating synthetically useful alpha-aryl carboxylic acid derivatives in good enantiomeric excess. The method can also be applied to enantioselective alkenylation reactions.
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