Journal
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
Volume 21, Issue 1, Pages 51-60Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.5435/JAAOS-21-01-51
Keywords
-
Categories
Ask authors/readers for more resources
Iliac crest bone graft has long been the standard adjunct used in 1 spine fusion surgery. This graft provides osteogenic, osteoinductive, and osteoconductive elements that aid in creation of a fusion mass. However, morbidity associated With bone graft harvest has led surgeons to seek other potential adjuncts, including, bone morphogenetic proteins, demineralized bone matrix, and graft expanders such as synthetic bone graft-and allograft. Knowledge of fusion biology is required to understand the benefits and limitations of these agent's, which promote fusion via one of four mechanisms: osteogenesis, osteoinduction, osteoconduction, and osteopromotion. Although bone morphogenetic proteins have shown a clear ability to aid in bone formation and successful fusion, recent concern regarding their safety has tempered enthusiasm regarding their use.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available