Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 67, Issue 6, Pages -Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2012.07.032
Keywords
children; double-strand break DNA repair; hereditary; nucleotide excision repair; photoaggravated; photodermatoses; photosensitivity; phototesting
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Photosensitivity disorders in children encompass a diverse group of diseases. Some inherited disorders manifest with photosensitivity early in life. Specific extracutaneous association may be the clue to diagnosis in this group of pediatric photodermatoses. Part II of this 2-part review covers hereditary photodermatoses caused by defects in nucleotide excision repair, double strand break repair, or localized or systemic biochemical abnormalities. Diagnosis and management of photoaggravated dermatoses are also discussed. Sun protection strategies are required in all patients with evidence of photosensitivity. Early recognition and prompt diagnosis is essential to minimize the long-term complications associated with inadequate photoprotection. (J Am Acad Dermatol 2012; 67:1113.e1e15.)
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