Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 62, Issue 4, Pages 605-610Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2009.06.084
Keywords
antimicrobial agents; Fentichlor; pesticides; photoallergic contact dermatitis; sunscreens
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Background: Retrospective chart reviews are periodically needed to update allergen series to detect changes in photoallergic contact dermatitis (PACD) over time. Objective: We sought to evaluate photopatch test results during a 13-year period and extend the observations to 20 years. Methods: A retrospective chart review was conducted in patients who were photopatch tested. Results: In all, 76 patients were evaluated A total of 69 positive photopatch and 45 positive patch test reactions were detected in 30 and 23 patients, respectively. The frequencies of the positive photopatch test reactions were Sunscreens 23.2%, antimicrobial agents 23.2%, medications 20.3%, fragrances 13%, plants and plant derivatives 11.6%, and pesticides 8.7%. Of the positive photopatch reactions to antimicrobial agents, 60% were caused by Fentichlor. Limitations: This study was a retrospective chart analysis, and the number of patients was small. Conclusions: Sunscreens and antimicrobial agents were the most frequent allergens eliciting PACD, and there was a decrease in PACD caused by fragrances. The number of reactions to medications increased. This Study also demonstrated that pesticides can be a cause of PACD. The detection of reactions to Fentichlor was unexpected and, although they have been attributed in some Studies to cross-reactions to sulfanilamides and bithionol, Such a robust association was not observed in this Study. This Study extends Our experience of the changes in the allergens that elicit PACD to 20 years. (J Am Acad Dermatol 2010;62:605-10.)
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