Journal
PLASMA SOURCES SCIENCE & TECHNOLOGY
Volume 24, Issue 3, Pages -Publisher
IOP Publishing Ltd
DOI: 10.1088/0963-0252/24/3/033001
Keywords
cold atmospheric plasma; cancer therapy; plasma selectivity
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Funding
- Dr Cyrus and Myrtle Katzen Cancer Research Center grant
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Plasma medicine is a relatively new field that grew from research in application of low-temperature (or cold) atmospheric plasmas in bioengineering. One of the most promising applications of cold atmospheric plasma (CAP) is cancer therapy. Convincing evidence of CAP selectivity towards the cancer cells has been accumulated. This review summarizes the state of the art of this emerging field, presenting various aspects of CAP application in cancer such as the role of reactive species (reactive oxygen and nitrogen), cell cycle modification, in vivo application, CAP interaction with cancer cells in conjunction with nanoparticles, and computational oncology applied to CAP.
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