Journal
JOURNAL OF SURGICAL RESEARCH
Volume 181, Issue 2, Pages 262-271Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jss.2013.02.002
Keywords
ALA; Aminolevulinic acid; Cancer; Fluorescence; Photodynamic
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Aminolevulinic acid (ALA) is a heme precursor that may have potential applications for photodynamic detection and photodynamic therapy-based treatment of solid tumors in a variety of malignancies. ALA may have a role in other applications in surgical oncology based on its ability to discriminate neoplastic tissue from adjacent normal tissue. In this review, we provide a comprehensive summary of the published studies of ALA in non-cutaneous solid malignancies. (C) 2013 Elsevier Inc. All rights reserved.
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