Journal
JOURNAL OF SURGICAL ONCOLOGY
Volume 107, Issue 4, Pages 433-445Publisher
WILEY
DOI: 10.1002/jso.23220
Keywords
diffuse type giant cell tumor; pigmented villonodular synovitis; giant cell tumor of tendon sheath; nodular tenosynovitis; synovectomy; radiation; isotopes; imatinib
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Giant cell tumors deriving from synovium are classified into a localized (GCT of tendon sheath; GCT-TS) and diffuse form (diffuse-type GCT, Dt-GCT). We propose a multidisciplinary management based upon a systematic review and authors' opinion. Open excision for GCT-TS and open synovectomy (plus excision) for Dt-GCT is advised to reduce the relatively high recurrence risk. External beam radiotherapy should be considered in severe cases, as Dt-GCT commonly extends extra-articular. J. Surg. Oncol. 2013;107:433445. (c) 2012 Wiley Periodicals, Inc.
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