Bile Cultures: A Guide to Infectious Complications After Pancreaticoduodenectomy

Background: The aim of this study was to evaluate the utility of intraoperative bile cultures on the outcome of patients undergoing pancreaticoduodenectomy Study Design: A review of a hepato-pancreato-biliary database was performed to identify all patients who had a pancreaticoduodenectomy from 1/1998 to 8/2008 Results: Two hundred twenty-eight patients were evaluated, with preoperative biliary stenting performed in 129 out of 229 patients (57%), with 63/129(49%) had bile cultures taken intraoperatively, 39/129(30%) having positive bile cultures Neither preoperative biliary stenting (incidence of complication 54% with stem vs 51% without. P = 0 9) nor positive bile culture (incidence of complication 54% with positive bile culture vs 53% without. P = 0 9) were predictors of overall complications Length of operating time, length of hospital stay, blood loss, blood transfusion. and severity of complications were similar in the group with and without stem There were 19 different organisms identified with not a single species was a statistically significant predictor of neither severity of complication nor increased length of stay Conclusions: Preoperative biliary stenting correlates with similar rate of biliary infections, however. intraoperative bile culture allows for early appropriate antibiotic use, which maintains a similar morbidity and infectious incidence as in patients without stents J. Surg Oncol 2010,102-478-481 (C) 2010 Wiley-Liss, Inc