Journal
JOURNAL OF SURGICAL ONCOLOGY
Volume 100, Issue 2, Pages 169-177Publisher
WILEY
DOI: 10.1002/jso.21280
Keywords
regional metastatic melanoma; isolated limb infusion; regional chemotherapy; melphalan; actinomycin-D; hypoxia
Funding
- Haak Bastiaanse-Kuneman Stichting
- Stichting Fundtie van de Vrijvrouwe van Renswoude te's-Gravenhage
- Stichting Sacha Swarttouw-Heijmans
- KWF Kankerbestrijding
- Stichting Prof. Michael-van Vloten Fonds
- Melanoma Foundation Of the University of Sydney
- University Medical Center Groningen/Faculty of Medical Sciences of the University of Groningen
Ask authors/readers for more resources
Isolated limb perfusion is the preferred treatment option for locally advanced melanoma and sarcoma confined to a limb. This treatment results in high response rates with a satisfying duration of response in hot tumours. A drawback of isolated limb perfusion, however, is the invasive and complex character of the procedure. Isolated limb infusion has been designed as a minimally invasive alternative to isolated limb perfusion. Treatment results of this simple technique reported by Various centres worldwide. show comparable response rates for melanoma and sarcoma. Therefore isolated limb infusion may replace isolated limb perfusion in the future as the preferred treatment option for these locally advanced limb tumours. J. Surg. Oncol. 2009;100:109-177. (C) 2009 Wiley-Liss, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available