4.5 Article

Determination by GC-IT/MS of Phytosterols in Herbal Medicinal Products for the Treatment of Lower Urinary Tract Symptoms and Food Products Marketed in Europe

Journal

PLANTA MEDICA
Volume 81, Issue 7, Pages 613-620

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0035-1545906

Keywords

gas chromatography ion trap mass spectrometry; (7)-phytosterols; pumpkin seed extracts; saw palmetto extracts; lower urinary tract symptoms (LUTS)

Funding

  1. Omega Pharma Manufacturing GmbH & Co. KG, Herrenberg, Germany

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A method for the determination of phytosterols in herbal medicinal products for the treatment of lower urinary tract symptoms and food products is described here. Using a convenient sample preparation protocol and sensitive gas chromatography ion trap mass spectrometry analysis, ten different sterols, among them five (7)-phytosterols as typical constituents of pumpkin seed preparations, could be identified and quantified. This protocol was applied to the analysis of 31 marketed products, from which seven were raw materials.

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