Journal
APPLIED PHYSICS LETTERS
Volume 106, Issue 21, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.4921754
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Funding
- National Natural Science Foundation of China [11035005, 11005126, 50876101]
- Hefei Institutes of Physical Science, Chinese Academy of Sciences (CASHIPS) Dean Funds [YZJJ201331]
- City University of Hong Kong Strategic Research Grant (SRG) [7004188]
- Hong Kong Research Grants Council (RGC) General Research Funds (GRF) [CityU 112212]
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The dynamics of gene expression regulation (at transcription level) in Staphylococcus aureus after different doses of atmospheric-pressure room-temperature air plasma treatments are investigated by monitoring the quantitative real-time polymerase chain reaction. The plasma treatment influences the transcription of genes which are associated with several important bio-molecular processes related to the environmental stress resistance of the bacteria, including oxidative stress response, biofilm formation, antibiotics resistance, and DNA damage protection/repair. The reactive species generated by the plasma discharge in the gas phase and/or induced in the liquid phase may account for these gene expression changes. (C) 2015 AIP Publishing LLC.
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