A highly sensitive nonenzymatic glucose sensor based on nickel oxide-carbon nanotube hybrid nanobelts

In this study, we demonstrated a highly sensitive electrochemical sensor for the determination of glucose in alkaline aqueous solution by using nickel oxide single-walled carbon nanotube hybrid nanobelts (NiO-SWCNTs) modified glassy carbon electrode (GCE). The hybrid nanobelts were prepared by the deposition of SWCNTs onto the Ni(SO4)(0.3)(OH)(1.4) nanobelt surface, followed by heat treatment at different temperatures ranging from 400 A degrees C to 600 A degrees C. The NiO-SWCNTs hybrid nanobelts modified electrode prepared at 500 A degrees C displays enhanced electrocatalytic activity towards glucose oxidation, revealing a synergistic effect between the NiO and the deposited SWCNTs. The as-fabricated nonenzymatic glucose sensor exhibits excellent glucose sensitivity (2,980 mu A cm(-2) mM(-1)), lower detection limit (0.056 mu M, signal/noise [S/N] ratio = 3), and wider linear range (0.5-1,300 mu M). Moreover, the sensor has been successfully used for the assay of glucose in serum samples with good recovery, ranging from 96.4 % to 102.4 %.