Magnetic nanoparticles for power absorption: Optimizing size, shape and magnetic properties

We present a Study on the magnetic properties of naked and silica-coated Fe(3)O(4) nanoparticles with sizes between 5 and 110 nm. Their efficiency as heating agents was assessed through specific power absorption (SPA) measurements as a function of particle size and shape. The results show a strong dependence of the SPA with the particle size, with a maximum around 30 nm, as expected for a Neel relaxation mechanism in single-domain particles. The SiO(2) shell thickness was found to play an important role in the SPA mechanism by hindering the heat Outflow, thus decreasing the heating efficiency. It is concluded that a compromise between good heating efficiency and surface functionality for biomedical purposes can be attained by making the SiO(2) functional coating as thin as possible. (C) 2009 Elsevier Inc. All rights reserved.