Journal
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
Volume 63, Issue 3, Pages 416-424Publisher
SPRINGER
DOI: 10.1007/s10971-012-2803-x
Keywords
Hierarchically pore silica; Bio-glasses; Plant template; Drug release; Osteogenic property
Categories
Funding
- National Native Science Foundation of China [20871037, 21171045, 21101046]
- Innovation special fund of Harbin Science and Technology Bureau of China [2010RFXXS055]
- Program for Scientific and Technological Innovation team Construction in Universities of Heilongjiang province [2011TD010]
- Doctoral Initiation Fund of Harbin Normal University [KGB201006]
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A series of highly ordered hierarchically porous silica and bio-glasses materials with macropore size of 8-1,000 mu m and mesopore size of 3.1-5.6 nm have been synthesized using six plant based materials as templates. However, the as-obtained porous structure was reported for the first time with interconnected 3D macropore up to 1,000 mu m. The porous silica materials were used as the host for drug loading and release, which showed a good sustained delivery function. The as-synthesized bio-glasses materials indicated the highly bioactive capability in the bone regeneration. This method can be utilized to synthesize other multi-porous bioactive glasses using different plants as templates for bone tissue repairing.
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