Journal
PLANT CELL
Volume 27, Issue 2, Pages 349-360Publisher
AMER SOC PLANT BIOLOGISTS
DOI: 10.1105/tpc.114.135186
Keywords
-
Funding
- National Natural Science Foundation of China [31430013, 31222029, 912173023]
- State Key Basic Research Program of China [2013CB127000]
- Shanghai Pujiang Program [12PJ1409900]
- Recruitment Program of Global Expects (China)
- National Key Laboratory of Plant Molecular Genetics Key Research Program
- Ministry of Education, Youth, and Sports, Czech Republic [LO1204]
- Swedish Governmental Agency for Innovation Systems
- Swedish Research Council
Ask authors/readers for more resources
Plant cells are totipotent and competent to regenerate from differentiated organs. It has been shown that two phytohormones, auxin and cytokinin, play critical roles within this process. As in animals, the regenerative capacity declines with age in plants, but the molecular basis for this phenomenon remains elusive. Here, we demonstrate that an age-regulated microRNA, miR156, regulates shoot regenerative capacity. As a plant ages, the gradual increase in miR156-targeted SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factors leads to the progressive decline in shoot regenerative capacity. In old plants, SPL reduces shoot regenerative capacity by attenuating the cytokinin response through binding with the B-type ARABIDOPSIS RESPONSE REGULATORs, which encode the transcriptional activators in the cytokinin signaling pathway. Consistently, the increased amount of exogenous cytokinin complements the reduced shoot regenerative capacity in old plants. Therefore, the recruitment of age cues in response to cytokinin contributes to shoot regenerative competence.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available