Journal
JOURNAL OF SEPARATION SCIENCE
Volume 36, Issue 6, Pages 1149-1167Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.201201090
Keywords
Application of enzymes; Biocatalysts; Enzyme kinetics; Flow-through bioreactors; Immobilized enzymes; Monoliths
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Funding
- Russian Foundation of Basic Researches (RFBR) [11-03-00829-a]
- Saint-Petersburg State University [12.39.1048.2012]
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In the last decade, the application of monolithic materials has rapidly expanded to the realization of flow-through bioconversion processes. Up to these days, different classes of enzymes such as hydrolases, lyases, and oxidoreductases have been immobilized on organic, inorganic, or hybrid monolithic materials to prepare the effective flow-through enzymes reactors for application in proteomics, biotechnology, pharmaceutics, organic synthesis, and biosensoring. Current review describes the results of kinetic study and specialties of flow-through immobilized enzyme reactors based on the existing monolithic materials.
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