Immobilization of cellulose phenylcarbamate onto silica gel via intermolecular polycondensation of triethoxysilyl groups introduced with (3-glycidoxypropyl)triethoxysilane

Cellulose 3,5-dimethylphenylcarbamate was successfully immobilized onto bare silica gel for HPLC through the intermolecular polycondensation of triethoxysilyl groups, which were introduced onto the cellulose derivative via epoxide ring-opening reaction under acidic conditions. The immobilized-type chiral packing material (CPM) exhibited high chiral recognition ability and could be used with various eluents, which are incompatible with the conventional CPMs prepared by coating the derivative onto silica gel.