Journal
JOURNAL OF SEPARATION SCIENCE
Volume 31, Issue 10, Pages 1694-1701Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.200700602
Keywords
column efficiency; enrofloxacin imprinted polymer; monolithic column; RAFT-mediated polymerization
Categories
Ask authors/readers for more resources
Molecularly imprinted monolithic columns for selective separation of enrofloxacin were prepared by Reversible Addition-Fragmentation Chain Transfer (RAFT)-mediated radical polymerization. Different ratios of initiation system were used in the synthesis. The structures of the monoliths were characterized to study the relationship between the synthetic conditions and morphology of the monolithic material. The separation performance of the monoliths was evaluated by liquid chromatography. Under optimized synthetic conditions, a monolithic molecularly imprinted polymer (MIP) with high selectivity and improved column efficiency was obtained. The research has shown that RAFT polymerization provides more adjustable conditions for making monolithic materials with different morphologies. The results also demonstrated that homogeneous macro-pore size distribution and large specific surface area are the key factors providing good separation ability and column efficiency for MIP monolithic structures.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available