Journal
PLACENTA
Volume 36, Issue 2, Pages 250-252Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.placenta.2014.11.020
Keywords
miR-106a similar to 363; Placenta; Preeclampsia
Funding
- Natural Science Foundation of China [30901779, 81274093]
- Natural Science Foundation of Shandong Province [ZR2013CM032, ZR2011CL015]
- Shandong Province Outstanding Youth Scientist foundation plan [BS2013YY020]
- Weifang Medical University [K1302021]
- Weifang Science and Technology Bureau [201301078]
Ask authors/readers for more resources
Preeclampsia (PE) is the leading cause of maternal and perinatal mortality and morbidity. MicroRNAs are strongly implicated in the pathogenesis of this syndrome. In current study, we performed a microarray assay to explore miRNA expression profile in the placenta, and found 11 upregulated and 7 downregulated miRNAs in preeclampsia. miR-363, plus other 5 member of miR-106a similar to 363 cluster was further examined and validated. These findings would facilitate further investigation of aberrant expression of miRNAs in the pathology of preeclampsia. (C) 2014 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available