Journal
PHYTOCHEMISTRY LETTERS
Volume 13, Issue -, Pages 297-301Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2015.07.003
Keywords
Aglaia eximia; Exiamiamide A; Exiamiamide B; Meliaceae; Cytotoxic activity
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Funding
- Third World Academic Sciences (TWAS) by US [12-006 RG/CHE/AS_G-UNESCO FR:3240271335]
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Two new bisamide compounds, eximiamide A (1) and eximiamide B (2) were isolated from the bark of Aglaia eximia (Meliaceae). The chemical structures of the new compound were elucidated on the basis of spectroscopic data. All of the compounds were evaluated for their cytotoxic effects against P-388 murine leukemia cells. Compounds 1 and 2 exhibited cytotoxic activity against P-388 murine leukemia cells with IC50 values of 7.6 and 8.5 mg/mL, respectively. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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