Journal
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
Volume 32, Issue 4, Pages 202-208Publisher
INFORMA HEALTHCARE
DOI: 10.3109/10799893.2012.692119
Keywords
Dopamine D2 receptor; receptor-receptor interactions; marine sponges
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The evidence for the existence of receptor heteromers opens up a new field for a better understanding of neural transmission. Based on our theory, we have discovered main triplets of amino acid residues in cell-adhesion receptors of marine sponges, which appear also as homologies in several dopamine D2 receptor heteromers of human brain. The obtained results probably mean a general molecular mechanism for receptor-receptor interactions in heteromers originated from the lowest animals (marine sponges).
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