Journal
JOURNAL OF PSYCHOSOMATIC RESEARCH
Volume 64, Issue 6, Pages 583-587Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpsychores.2008.02.020
Keywords
irritable bowel syndrome; sex; gender
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Funding
- NINR NIH HHS [NR01094, P30 NR04001] Funding Source: Medline
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In industrialized parts of the world, women seek health care services for irritable bowel syndrome (IBS) more frequently than men. The role of gender in IBS is likely multifactorial involving inherent physiological differences in gonadal hormones, stress reactivity, and inflammatory responses, as well as sociocultural differences in response to pain and/or bowel pattern changes. This mini-review in particular addresses gender differences in visceral sensitivity, motility, and autonomic nervous system balance as potential factors contributing to gender differences in IBS presentation. (C) 2008 Elsevier Inc. All rights reserved.
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