Related references
Note: Only part of the references are listed.Safety, tolerability, pharmacokinetics and pharmacodynamics of losmapimod following a single intravenous or oral dose in healthy volunteers
April M. Barbour et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study
T. Ostenfeld et al.
EUROPEAN JOURNAL OF PAIN (2013)
The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications
S. Moylan et al.
MOLECULAR PSYCHIATRY (2013)
A Randomized Controlled Trial of the Tumor Necrosis Factor Antagonist Infliximab for Treatment-Resistant Depression
Charles L. Raison et al.
JAMA PSYCHIATRY (2013)
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
Michael Maes et al.
BMC MEDICINE (2012)
Molecular adaptation to chronic antidepressant treatment: evidence for a more rapid response to the novel α2-adrenoceptor antagonist/5-HT-noradrenaline reuptake inhibitor (SNRI), S35966, compared to the SNRI, venlafaxine
Florence Serres et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2012)
Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression
Yang Liu et al.
JOURNAL OF AFFECTIVE DISORDERS (2012)
An Oral Inhibitor of p38 MAP Kinase Reduces Plasma Fibrinogen in Patients With Chronic Obstructive Pulmonary Disease
David A. Lomas et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2012)
Association of a polymorphism in the indoleamine-2,3-dioxygenase gene and interferon-α-induced depression in patients with chronic hepatitis C
A. K. Smith et al.
MOLECULAR PSYCHIATRY (2012)
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression
Brian Leonard et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2012)
Interleukin-6, C-reactive protein and interleukin-10 after antidepressant treatment in people with depression: a meta-analysis
S. A. Hiles et al.
PSYCHOLOGICAL MEDICINE (2012)
Effects of p38 Mitogen-Activated Protein Kinase Inhibition on Vascular and Systemic Inflammation in Patients With Atherosclerosis
Maysoon Elkhawad et al.
JACC-CARDIOVASCULAR IMAGING (2012)
Inhibition of p38 Mitogen-Activated Protein Kinase Improves Nitric Oxide-Mediated Vasodilatation and Reduces Inflammation in Hypercholesterolemia
Joseph Cheriyan et al.
CIRCULATION (2011)
The new '5-HT' hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
M. Maes et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2011)
A Meta-Analysis of Cytokines in Major Depression
Yekta Dowlati et al.
BIOLOGICAL PSYCHIATRY (2010)
Plasma Protein Biomarkers for Depression and Schizophrenia by Multi Analyte Profiling of Case-Control Collections
Enrico Domenici et al.
PLOS ONE (2010)
Effects of eicosapentaenoic acid and fluoxetine on plasma cortisol, serum interleukin-1 beta and interleukin-6 concentrations in patients with major depressive disorder
Shima Jazayeri et al.
PSYCHIATRY RESEARCH (2010)
Summing nondetects: Incorporating low-level contaminants in risk assessment
Dennis R Helsel
Integrated Environmental Assessment and Management (2010)
Activation of Central Nervous System Inflammatory Pathways by Interferon-Alpha: Relationship to Monoamines and Depression
Charles L. Raison et al.
BIOLOGICAL PSYCHIATRY (2009)
Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity
Daniel Lindqvist et al.
BIOLOGICAL PSYCHIATRY (2009)
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
Andrew H. Miller et al.
BIOLOGICAL PSYCHIATRY (2009)
Cytokine-induced depression during IFN-α treatment: The role of IL-6 and sleep quality
Aric A. Prather et al.
BRAIN BEHAVIOR AND IMMUNITY (2009)
CLINICAL TRIAL OF ADJUNCTIVE CELECOXIB TREATMENT IN PATIENTS WITH MAJOR DEPRESSION: A DOUBLE BLIND AND PLACEBO CONTROLLED TRIAL
Shahin Akhondzadeh et al.
DEPRESSION AND ANXIETY (2009)
Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals?
Lucile Capuron et al.
JOURNAL OF AFFECTIVE DISORDERS (2009)
Interferon-γ and Tumor Necrosis Factor-α Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin
Jason C. O'Connor et al.
JOURNAL OF NEUROSCIENCE (2009)
Increased soluble tumor necrosis factor-alpha receptors in patients with major depressive disorder
Rodrigo Grassi-Oliveira et al.
PSYCHIATRY AND CLINICAL NEUROSCIENCES (2009)
Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis
M. Bryant Howren et al.
PSYCHOSOMATIC MEDICINE (2009)
A detailed examination of cytokine abnormalities in Major Depressive Disorder
N. M. Simon et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2008)
Depression, comorbidities and the TNF-α system
H. Himmerich et al.
EUROPEAN PSYCHIATRY (2008)
Sustained low-grade pro-inflammatory state in unmedicated, remitted women with major depressive disorder as evidenced by elevated serum levels of the acute phase proteins c-reactive protein and serum amyloid a
Mitchel A. Kling et al.
BIOLOGICAL PSYCHIATRY (2007)
Bayesian modelling and ROC analysis to predict placebo responders using clinical score measured in the initial weeks of treatment in depression trials
Roberto Gomeni et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2007)
Successful antidepressant therapy restores the disturbed interplay between TNF-α system and HPA axis
Hubertus Himmerich et al.
BIOLOGICAL PSYCHIATRY (2006)
The association between C-reactive protein levels and depression:: Results from the Northern Finland 1966 Birth Cohort study
Timo Liukkonen et al.
BIOLOGICAL PSYCHIATRY (2006)
Plasma levels of adiponectin and tumor necrosis factor-alpha in patients with remitted major depression receiving long-term maintenance antidepressant therapy
Kosuke Narita et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2006)
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression
Carlos A. Zarate et al.
ARCHIVES OF GENERAL PSYCHIATRY (2006)
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression:: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine
N Müller et al.
MOLECULAR PSYCHIATRY (2006)
Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study
Julien Mendlewicz et al.
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY (2006)
Interleukin-6: discovery of a pleiotropic cytokine
Tadamitsu Kishimoto
ARTHRITIS RESEARCH & THERAPY (2006)
The many paths to p38 mitogen-activated protein kinase activation in the immune system
Jonathan D. Ashwell
NATURE REVIEWS IMMUNOLOGY (2006)
Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial
S Tyring et al.
LANCET (2006)
Cytokines sing the blues: inflammation and the pathogenesis of depression
CL Raison et al.
TRENDS IN IMMUNOLOGY (2006)
Excessive daytime sleepiness in a general population sample: The role of sleep apnea, age, obesity, diabetes, and depression
EO Bixler et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
IDO and interferon-α-induced depressive symptoms:: a shift in hypothesis from tryptophan depletion to neurotoxicity
MC Wichers et al.
MOLECULAR PSYCHIATRY (2005)
Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: Clinical implications
S Alesci et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Cytokines as mediators of depression: What can we learn from animal studies?
AJ Dunn et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2005)
Raised plasma levels of tumor necrosis factor α in patients with depression -: Normalization during electroconvulsive therapy
KA Hestad et al.
JOURNAL OF ECT (2003)
Mild depressive symptoms are associated with amplified and prolonged inflammatory responses after influenza virus vaccination in older adults
R Glaser et al.
ARCHIVES OF GENERAL PSYCHIATRY (2003)
Item banking to improve, shorten and computerize self-reported fatigue: An illustration of steps to create a core item bank from the FACIT-Fatigue Scale
JS Lai et al.
QUALITY OF LIFE RESEARCH (2003)
Association between depression and elevated C-reactive protein
M Danner et al.
PSYCHOSOMATIC MEDICINE (2003)
Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder
C Tuglu et al.
PSYCHOPHARMACOLOGY (2003)
Cytokine and cytokine receptor pleiotropy and redundancy
K Ozaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis
O Mikova et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2001)
Cytokine-associated emotional and cognitive disturbances in humans
A Reichenberg et al.
ARCHIVES OF GENERAL PSYCHIATRY (2001)
Cytokine production and treatment response in major depressive disorder
S Lanquillon et al.
NEUROPSYCHOPHARMACOLOGY (2000)