Journal
JOURNAL OF PROTEOMICS
Volume 72, Issue 6, Pages 928-935Publisher
ELSEVIER
DOI: 10.1016/j.jprot.2009.01.027
Keywords
Antibody microarrays; Recombinant antibodies; Disease proteomics; Proteomics; Expression profiling
Categories
Funding
- Crafoord foundation
- Greta and Johan Kocks foundation
- Swedish foundation
- Swedish National Science Council (VR-NT)
- Osterlund foundation
Ask authors/readers for more resources
Antibody-based microarray is a novel proteomic technology setting a new standard for molecular profiling of non-fractionated complex proteomes. The first generation of antibody microarrays has already demonstrated its potential for generating detailed protein expression profiles, or protein atlases, of human body fluids in health and disease, paving the way for new discoveries within the field of disease proteomics. The process of designing highly miniaturized, high-density and high-performing antibody microarray set-ups have, however, proven to be challenging. in this mini-review we discuss key technological issues that must be addressed in a cross-disciplinary manner before true global proteome analysis can be performed using antibody microarrays. (C) 2009 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available