Journal
PHYSIOLOGY & BEHAVIOR
Volume 152, Issue -, Pages 422-430Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.physbeh.2015.06.017
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Funding
- National Institute on Deafness and Communications Disorders [DC-06360]
- Oklahoma Center for the Advancement of Science and Technology Health Research Program [HR-09-123]
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Regulation of appropriate osmolality of body fluid is critical for survival, yet there are sex differences in-compensatory responses to osmotic challenges. Few studies have focused on the role of sex hormones such as estradiol in behavioral responses to increases or decreases in systemic osmolality, and even fewer studies have investigated whether central actions of estrogens contribute to these responses. This overview integrates findings from a series of ongoing and completed experiments conducted in my laboratory to assess estradiol effects on water and NaCl intake in response to osmotic challenges, and on activity in central pathways that mediate such responses. (C) 2015 Elsevier Inc All rights reserved.
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