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The Survival Mechanisms of Thermophiles at High Temperatures: An Angle of Omics

Journal

PHYSIOLOGY
Volume 30, Issue 2, Pages 97-106

Publisher

AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00066.2013

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Funding

  1. 973 program [2010CB912703]
  2. Nature Science Foundations of China [30800023]
  3. Beijing Municipal Natural Science Foundation [5132023]

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Thermophiles are referred to as microorganisms with optimal growth temperatures of >60 degrees C. Over the past few years, a number of studies have been conducted regarding themophiles, especially using the omics strategies. This review provides a systematic view of the survival physiology of thermophiles from an omics perspective, which suggests that the adaptive ability of thermophiles is based on a cooperative mode with multi-dimensional regulations integrating genomics, transcriptomics, and proteomics.

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