Journal
PHYSIOLOGY
Volume 30, Issue 1, Pages 30-39Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00024.2014
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Funding
- National Institutes of Health [GM-029090-30A1S1, 5K01 AR-55676, GM-29090-31]
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Previous studies have identified over 3,000 genes that are differentially expressed in male and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle fiber composition, myosin heavy chain expression, contractile function, and the regulation of these physiological differences by thyroid hormone, estrogen, and testosterone. The findings presented lay the basis for the continued work needed to fully understand the skeletal muscle differences between males and females.
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