Journal
PHYSIOLOGICAL MEASUREMENT
Volume 36, Issue 10, Pages -Publisher
IOP Publishing Ltd
DOI: 10.1088/0967-3334/36/10/2171
Keywords
bioimpedance; body composition; body fluids estimation
Categories
Funding
- Royal Institute of Technology (KTH)
- University of Boras (HB)
- Swedish association for Medical Technology (MTF)
Ask authors/readers for more resources
Determination of body fluids is a useful common practice in determination of disease mechanisms and treatments. Bioimpedance spectroscopy (BIS) methods are non-invasive, inexpensive and rapid alternatives to reference methods such as tracer dilution. However, they are indirect and their robustness and validity are unclear. In this article, state of the art methods are reviewed, their drawbacks identified and new methods are proposed. All methods were tested on a clinical database of patients receiving growth hormone replacement therapy. Results indicated that most BIS methods are similarly accurate (e.g. < 0.5 +/- 3.0% mean percentage difference for total body water) for estimation of body fluids. A new model for calculation is proposed that performs equally well for all fluid compartments (total body water, extra-and intracellular water). It is suggested that the main source of error in extracellular water estimation is due to anisotropy, in total body water estimation to the uncertainty associated with intracellular resistivity and in determination of intracellular water a combination of both.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available