Journal
JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS
Volume 49, Issue 12, Pages 832-864Publisher
WILEY
DOI: 10.1002/polb.22259
Keywords
biodegradable; biomaterials; polyamides; polycarbonates; polyesters; polyethers; polylactide; polyphosphazenes; polysaccharides; polyurethanes
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Funding
- NIAMS NIH HHS [R01 AR052536-06, R01 AR052536] Funding Source: Medline
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Utilization of polymers as biomaterials has greatly impacted the advancement of modern medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant advantage of being able to be broken down and removed after they have served their function. Applications are wide ranging with degradable polymers being used clinically as surgical sutures and implants. To fit functional demand, materials with desired physical, chemical, biological, biomechanical, and degradation properties must be selected. Fortunately, a wide range of natural and synthetic degradable polymers has been investigated for biomedical applications with novel materials constantly being developed to meet new challenges. This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications. (C) 2011 Wiley Periodicals, Inc. J PolymSci Part B: PolymPhys 49: 832-864, 2011
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