Journal
JOURNAL OF PHYSIOLOGY-PARIS
Volume 106, Issue 1-2, Pages 34-39Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jphysparis.2011.09.001
Keywords
Glial cells; Oligodendrocytes; Astrocytes; Gap junctions; Hemichannels; Connexins; Pannexins; Astroglial networks
Categories
Funding
- Ecole des Neurosciences de Paris
Ask authors/readers for more resources
In the brain, glia represents the cell population that expresses the highest level of connexins, the membrane protein constituents of gap junction channels and hemichannels. This statement has initially led to propose the existence of a glial syncytium. Since then, functional studies have established that connexin channel-mediated communication between glial cells was more restricted and plastic that primarily thought. In particular, this is the case for astrocytes that form functional networks of communicating cells. Altogether these findings lead to reconsider the interaction between neurons and glia that should not be solely studied at the single cell level but also at a more integrated level as the interplay between neuronal circuits and glial networks. (C) 2011 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available