Journal
JOURNAL OF PHYSIOLOGICAL SCIENCES
Volume 59, Issue 4, Pages 335-339Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s12576-009-0042-x
Keywords
Corticosteroids; Pleural effusion; Ussing system
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Funding
- Hellenic General Secretariat of Research and Technology [PENED 2003-03ED782]
- ARITI S.A
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The effect of dexamethasone on the transmesothelial electrical resistance (R (TM)) of sheep pleura was investigated by Ussing chamber experiments. Our results show that dexamethasone decreases the R (TM) of sheep pleurae, in part by stimulation of glucocorticoid receptors. This finding may be of importance in regard to the faster resolution of corticosteroid-treated pleural effusions.
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