Journal
JOURNAL OF PHYSICS-CONDENSED MATTER
Volume 24, Issue 16, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0953-8984/24/16/164208
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Funding
- US National Human Genome Research Institute of the National Institutes of Health [1R21HG004764-01]
- US Department of Energy (DOE) at ORNL [DEAC05-00OR22725]
- US DOE
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The recently demonstrated functionality of an aqueous quadrupole micro-or nano-trap opens a new avenue for applications of Paul traps, like confinement of a charged biomolecule which requires a water environment for its chemical stability. Besides the strong viscosity forces, the motion of a charged particle in the aqueous trap is subject to dielectrophoretic and electrophoretic forces. In this study, we describe the general conditions for stability of a charged particle in an aqueous quadrupole trap. We find that for typical micro-trap parameters, the effects of both dielectrophoresis and electrophoresis significantly influence the trap stability. In particular, an aqueous quadrupole trap could play the role of a synthetic virtual nanopore for the third generation of DNA sequencing technology.
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