The transverse Ising model: a guide for combined modalities of hyperthermia and imaging

We provide a simple theoretical framework using the transverse Ising model to understand heat dissipation when magnetic fluid hyperthermia is performed in conjunction with magnetic resonance imaging. This combined modality is of immense utility in remedial procedures for cancer, but observations related to decreased heat dissipation have cast doubt on its applicability in a clinical laboratory. Through a first-principle analysis, we provide practical procedures for eliminating this problem by easy manipulation of laboratory parameters. Their usage has been largely empirical to date. Our calculations provide a firm grounding to the ad hoc methodologies and are a significant step towards placing the combined modality in the mainstream of cancer remedy.