Journal
PHYSICAL REVIEW LETTERS
Volume 114, Issue 9, Pages -Publisher
AMER PHYSICAL SOC
DOI: 10.1103/PhysRevLett.114.098102
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Funding
- Swedish Research Council
- Knut and Alice Wallenberg Foundation
- European Research Council
- Rontgen-Angstrom Cluster
- Stiftelsen Olle Engkvist Byggmastare
- Max Planck Society
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We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.
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