4.8 Article

Boosting Dissolution Dynamic Nuclear Polarization by Cross Polarization

Journal

JOURNAL OF PHYSICAL CHEMISTRY LETTERS
Volume 4, Issue 1, Pages 111-114

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jz301781t

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Funding

  1. Swiss National Science Foundation
  2. Ecole Polytechnique Federale de Lausanne (EPFL)
  3. Swiss Commission for Technology and Innovation (CTI), Bruker BioSpin Switzerland AG
  4. French CNRS

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The efficiency of dissolution dynamic nuclear polarization can be boosted by Hartmann-Hahn cross polarization at temperatures near 1.2 K. This enables high throughput of hyperpolarized solutions with substantial gains in buildup times and polarization levels. During dissolution and transport, the C-13 nuclear spin polarization P(C-13) merely decreases from 45 to 40%.

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