Journal
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
Volume 3, Issue 8, Pages 1024-1029Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jz300033g
Keywords
-
Categories
Funding
- NSF [CMMI-1054877, CMMI-0939523, CMMI-1030963]
- Office of Naval Research [N000141110767]
- Terry C. Johnson Center for Basic Cancer Research
- KSU
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [923499] Funding Source: National Science Foundation
- Div Of Civil, Mechanical, & Manufact Inn
- Directorate For Engineering [1030963] Funding Source: National Science Foundation
Ask authors/readers for more resources
By interfacing the quantum mechanical properties of nanomaterials with the complex processes in biology, several bio/nano systems have evolved with applications in biosensors, cellular devices, drug delivery, and biophotoluminescence. One recent breakthrough has been the application of graphene, a two-dimensional (2-D) sheet of sp(2) hybridized carbon atoms arranged in a honeycomb lattice, as a sensitive platform for interfacing with biological cells to detect intra- and extracellular phenomena, including cellular excretion and cell membrane's potential modulation. In this Perspective, we discuss the recent results on graphene/cell interfacial devices and the principles defining the modulation of charge-carrier properties in graphene and its derivatives via interaction with cellular membranes. Graphene's high sensitivity in these applications evolves from the pi-carrier cloud confined within an atom-thick layer, quantum-capacitance-induced doping enhancement, closely spaced electronic bands, and a large surface area. We discuss the effect of the electronegativity of the cell wall and the dynamic changes in its chemical potential on doping specific carriers into graphene. Finally, we discuss the challenges and opportunities of graphene-interfaced biocellular systems.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available