Journal
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
Volume 1, Issue 24, Pages 3446-3450Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jz101483u
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Funding
- Shanghai Pujiang Program [09PJ1403000]
- Research Fund for the Doctoral Program of Higher Education [20090074120009]
- Natural Science Foundation of China [51072053]
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High-density carboxyl groups have been successfully grafted onto the pore surface of mesoporous nanocarriers which served to complex with platinum atoms in cisplatin, leading to much increased drug loading efficiency, distinctly prolonged and pH-responsive cisplatin release, and greatly enhanced growth inhibition effect against MCF-7 and HeLa cancer cell lines.
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