Journal
JOURNAL OF PHYSICAL CHEMISTRY C
Volume 118, Issue 7, Pages 3708-3715Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jp4091393
Keywords
-
Funding
- Duke University Exploratory Research Funds
- Defense Advanced Research Projects Agency [HR0011-13-2-0003]
- National Institutes of Health [T32 EB001040]
Ask authors/readers for more resources
In the ongoing search for ever-brighter surface-enhanced Raman scattering (SERS) nanoprobes, gold nanostars (AuNSs) have emerged as one of the best geometries for producing SERS in a nonaggregated state. Despite their high enhancement factor, optical extinction from plasmon-matched nanoparticles can greatly attenuate the overall SERS intensity. Herein, we report the development of a new hybrid bimetallic NS-based platform that exhibits superior resonant SERS (SERRS) properties. In this new nanoplatform, coating AuNSs with a subtotal layer of silver (AuNS@Ag) can further increase their SERRS brightness by an order of magnitude when being interrogated by an off-resonant excitation source. Silica-encapsulated AuNS@Ag nanoprobes were injected intradermally into a rat pelt, where SERRS was readily detected with higher signal-to-noise than nanoprobes prepared from AuNS. Moreover, these off-resonance AuNS@Ag nanoprobes did not cause any gross photothermal damage to tissue, which was observed with the plasmon-matched AuNSs. This novel SERRS-active hybrid nanoprobe exhibits high SERRS brightness and offers I promising properties for future applications in sensing and molecular imaging.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available