Journal
JOURNAL OF PHYSICAL CHEMISTRY B
Volume 117, Issue 46, Pages 14367-14371Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jp4087656
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Funding
- National Natural Science Foundation of China [21101079, 21175034, 21371081, 21301073]
- MOST [2012BACO1B07, 2012AA06A303, 2012BAD29B04, 2012BAKI1B01, 2011BAK1OB07, 2011BAK10B01, 2010AA06Z302, 2010DFB3047, 2013ZX08012-001, 2012BAK17B10, 2012BAK08B01, 2012YQ090194, 2012BAD29B05, 2013AA065501]
- Jiangsu Province, MOF and MOE [NCET-12-0879, BE2011626, BE2013613, BE2013611, 201310128, 201210127, 201210036, 201310135, 311002, JUSRP513084]
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A MRI biosensor for sensitive and specific detection of lead ions (Pb2+) was developed based on DNAzyme-induced cleavage of magnetic nanoparticles (MNPs). A low limit of detection (LOD) of 0.05 ng mL-1 was obtained. This biosensor has the potential to serve as a general platform for the detection of heavy metal ions.
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