Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 62, Issue -, Pages 177-181Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jpba.2011.12.013
Keywords
THz time-domain spectroscopy; Far infrared; Genistein; Biochanin A
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Funding
- Research Foundation of the State Ethnic Affairs Commission of People's Republic of China [09ZY012]
- National Natural Science Foundation of China (NSFC) [11104360]
- United States National Science Foundation
- Division Of Physics
- Direct For Mathematical & Physical Scien [0757680] Funding Source: National Science Foundation
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The temperature dependent vibrational spectra of Genistein and Biochanin A, major components in Mongolian medicines Agi, in the range of 0.5-4.5 THz (16.7-150 cm(-1)) are presented for the first time. Over the temperature range from 295 to 77K, 12 highly resolved spectral features for the Genistein and 13 features for Biochanin A were measured by THz-TDS and display strong linewidth narrowing and frequency blue-shift with cooling. Such narrow-line THz fingerprint spectra provide a rapid, nondestructive and reliable method for the identification of these Chinese traditional medicines. (C) 2011 Elsevier B.V. All rights reserved.
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