4.6 Article

Isolation and structural elucidation of flibanserin as an adulterant in a health supplement used for female sexual performance enhancement

Journal

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 57, Issue -, Pages 104-108

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.jpba.2011.08.027

Keywords

Health supplement; Flibanserin; LC-LTQ Orbitrap XL FTMS; NMR

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A health supplement used for female sexual performance enhancement was sent to Health Sciences Authority of Singapore for testing. An unknown compound was detected and isolated from the health supplement and its structure was elucidated using LC-DAD, LC-FTMS, NMR and IR. The detected compound was identified to be flibanserin, a non-hormonal treatment developed for pre-menopausal woman with hypoactive sexual desire disorder (HSDD). (C) 2011 Elsevier B.V. All rights reserved.

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