Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 46, Issue 4, Pages 804-807Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpba.2007.12.004
Keywords
vardenafil analogue; erectile dysfunction; herbal product; PDE-5 inhibitor; liquid chromatography-mass spectrometry (LC-MS)
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A new herbal health product marketed for enhancing erectile function, namely Power58 Platinum, was purchased over-the-counter in Hong Kong. The product was tested for adulteration with sildenafil, tadalafil, and vardenafil as well as their structurally modified analogues. A new analogue of vardenafil, in which the N-ethylpiperazine ring and the sulphonyl group were removed from the vardenafil structure, was identified in the product. (C) 2007 Elsevier B.V. All rights reserved.
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