Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 46, Issue 5, Pages 882-891Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jpba.2007.06.008
Keywords
CHIRALPAK IC; cellulose tris(3,5-dichlorophenylcarbamate); immobilised polysaccharide-based chiral stationary phases; enantiomeric resolution by liquid chromatography
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CHIRALPAK IC is a new chiral stationary phase (CSP) made by immobilising cellulose tris(3,5-dichlorophenylcarbamate) on silica gel. The chiral selector is distinct from any other commercially available polysaccharide-based CSPs. Apart from its compatibility with the whole series of solvents; this CSP is able to operate under various chromatographic conditions and bring about new characteristics in enantiomeric recognition. It can afford many large and specific enantiomeric separations. It exhibits complementary properties with regard to the existing immobilised chiral packing materials of the same category. (C) 2007 Elsevier B.V. All rights reserved.
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