Journal
JOURNAL OF PEDIATRICS
Volume 202, Issue -, Pages 92-+Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2018.07.003
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Funding
- National Health and Medical Research Council (NHMRC) [1028422, 1060733, 606789, 1081288, 1085754]
- Monash University
- Murdoch Children's Research Institute
- MRC [MR/K004867/1, MC_UU_00005/7] Funding Source: UKRI
- National Health and Medical Research Council of Australia [1085754] Funding Source: NHMRC
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Objective To assess the effectiveness of Cogmed Working Memory Training compared with a placebo program in improving academic functioning 24 months post-training in extremely preterm/extremely low birth weight 7-year-olds. Study design A multicenter double-blind, placebo-controlled randomized controlled trial was conducted across all tertiary neonatal hospitals in the state of Victoria, Australia. Participants were 91 extremely preterm/extremely low birth weight 7-year-old children born in Victoria in 2005. Children were randomly assigned to either the Cogmed or placebo arm and completed the Cogmed or placebo program (20-25 sessions of 35-40 minutes duration) at home over 5-7 weeks. Academic achievement (word reading, spelling, sentence comprehension, and mathematics) was assessed 24 months post-training, as well as at 2 weeks and 12 months post-training, via standardized testing inclusive of working memory, attention, and executive behavior assessments. Data were analyzed using an intentionto-treat approach with mixed-effects modeling. Results There was little evidence of any benefits of Cogmed on academic functioning 24 months post-training, as well as on working memory, attention, or executive behavior at any age up to 24 months post-training compared with the placebo program. Conclusions We currently do not recommend administration of Cogmed for early school-aged children born extremely preterm/extremely low birth weight to improve academic functioning.
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