Journal
JOURNAL OF PEDIATRICS
Volume 162, Issue 6, Pages 1285-+Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2013.01.003
Keywords
-
Categories
Funding
- Grants-in-Aid for Scientific Research [23390269, 24659491] Funding Source: KAKEN
Ask authors/readers for more resources
A small fraction of cases of juvenile myelomonocytic leukemia (JMML) develop massive disease activation. Through genomic analysis of JMML, which developed in an individual with mosaicism for oncogenic KRAS mutation with rapid progression, we identified acquired uniparental disomy at 12p. We demonstrated that duplication of oncogenic KRAS is associated with rapid JMML progression.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
