Propranolol for the Treatment of a Life-Threatening Subglottic and Mediastinal Infantile Hemangioma

An infant with a subglottic hemangioma remained in respiratory distress after multiple treatments failed and was found to have an enlarging mediastinal infantile hemangioma compressing the trachea. Treatment with oral propranolol resulted in resolution of symptoms within 2 days and a 50% reduction in lesion size within 1 week. (J Pediatr 2010; 156: 335-8)