Journal
JOURNAL OF PEDIATRICS
Volume 155, Issue 2, Pages 250-253Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2009.02.038
Keywords
-
Categories
Ask authors/readers for more resources
Objective To evaluate whether adenotonsillectomy leads to complete resolution in children with PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) syndrome. Study design Thirty-nine children with PFAPA syndrome were randomized to either adenotonsillectomy (surgery group; n = 19) or expectant management (control group; n = 20). All patients were then invited prospectively to record all PFAPA episodes, and were evaluated clinically every 3 months for 18 months after randomization. Results The proportion of patients experiencing complete resolution was 63% in the surgery group and 5% in the control group (P < .001). The mean (standard deviation) number of episodes recorded during the study period was 0.7 +/- 1.2 in the surgery group and 8.1 +/- 3.9 in the control group (P < .001). The episodes were less severe in the surgery group. Conclusions Adenotonsillectomy is an effective treatment strategy for children with PFAPA syndrome. (J Pediatr 2009; 155:250-3).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available