Journal
JOURNAL OF PEDIATRIC SURGERY
Volume 43, Issue 12, Pages E25-E29Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.jpedsurg.2008.09.017
Keywords
Intestinal failure; Intestinal dysmotility; Interstitial cells of Cajal; C-kit
Categories
Funding
- Hospital for Sick Children (Toronto, Ontario, Canada)
- Department of Surgery, University of Toronto (Toronto, Ontario, Canada)
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Absence or altered distribution of the interstitial cells of Cajal (ICCs) has been described in association with intestinal pseudoobstruction in adults. We report the First pediatric case with regional absence of ICCs in the distal small bowel and colon associated with intestinal pseudoobstruction, This report highlights that abnormalities of the ICCs in intestinal pseudoobstruction should be considered early in the diagnostic workup of children with intestinal pseudoobstruction. (c) 2008 Elsevier Inc. All rights reserved.
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