Journal
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Volume 34, Issue 1, Pages 68-71Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MPH.0b013e31820e4636
Keywords
lymphoma B-cell; lymphoma follicular; testis; child; adolescence
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Funding
- Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Department of Health and Human Services [CA 13539, CA 98543]
- ARC (Association pour la Recherche contre le Cancer)
- La Ligue Nationale Contre Le Cancer
- Institut Gustave Roussy
- United Kingdom Cancer Research Campaign
- CCG
- POG
- NATIONAL CANCER INSTITUTE [U10CA098543, U10CA013539] Funding Source: NIH RePORTER
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This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.
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