Journal
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Volume 33, Issue 5, Pages 383-386Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MPH.0b013e3182172515
Keywords
Kasabach-Merritt syndrome; thrombocytopenia; consumptive coagulopathy; localized intravascular coagulation; hypofibrinogenemia
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Funding
- National Institutes of Health [K12RR01627]
- Doris Duke Charitable Foundation
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Consumptive coagulopathy is a known complication of large vascular tumors. We describe 2 episodes of consumptive coagulopathy in young children, which were secondary to isolated splenic vascular tumors. One child was successfully treated by subtotal embolization of the spleen, whereas the second child required splenectomy after an initial embolization improved-but did not fully control-his consumptive coagulopathy.
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